Endocrine Abstracts

Introduction: Amiodarone is an antiarrhythmic drug whose high iodine content may influence thyroid function. The first line treatment of amiodarone-induced hyperthyroidism (AIH) is mainly medical. Plasmapheresis has been used in cases of antithyroid intolerance or refractory hyperthyroidism, although clinical experience is poor.Clinical case: We present a case of a patient with structural heart disease and severe AIH refractory to medical treatment who r...

Introduction: Differentiation between Cushing’s disease (CD) and ectopic Cushing’s syndrome (ECS) remains a diagnostic challenge. Currently available tests lack sufficient sensitivity and specificity or are invasive and technically difficult. Recently, an ACTH-UFC index has been proposed to differentiate the two forms of ACTH dependent Cushing’s syndrome (CS) (Ding, 2021). This work aimed to confirm the diagnostic utility of the ACTH-UFC index to differentiate C...

Context: There is no data on mortality of acromegaly diagnosed in the elderly. Objective: To compare clinical characteristics, GH-related comorbidities, therapeutic approaches and mortality of patients diagnosed before or after 2010 and to assess overall mortality compared with the general Spanish population. Setting: Spanish tertiary care centers.Design, Patients, and Methods: Retrospective evaluation of 118...